Wednesday, January 03, 2007

Carnitine and Lipoic Acid= Reduction In Age-Related DNA Damage?

Lots of good news regarding lipoics and carnitines. This new study on PubMed offers more evidence of the r-lipoic acid / carnitine combination as the closest thing we have to anti-aging in a pill.

Titled: "Mitigation of age-dependent oxidative damage to DNA in rat heart by carnitine and lipoic acid." the study concludes: "Supplementation of carnitine and lipoic acid during aging process decreased the incidence of this DNA damage, therefore suggesting that this feeding regimen inhibits the accumulation of age-associated oxidative DNA damage."

While humans are not rats, this study offers real promise of the efficacy of the lipoic/carnitine combination.

As you would expect, Geronova was well ahead of every other company when they introduced their sustained release, highly bioavailable lipoics: Mito-Gold, R-PLUS and RALA-Gel in 2005. Last year they made available a revolutionary new carnitine/acetyl-l-carnitine product: Carnitine Plus.

Combining a Geronova engineered lipoic product with Carnitine Plus is the closest thing we currently have to true anti-aging at the cellular level.

R-Lipoic Acid Protects Against Toxins In Cigarette Smoke?

New research study on PubMed co-authored by the lipoic "godfather" Dr. Bruce Ames.

Study title: "Acrolein, a Toxicant in Cigarette Smoke, Causes Oxidative Damage and Mitochondrial Dysfunction in RPE Cells: Protection by (R)-{alpha}-Lipoic Acid."

"These experiments indicate that mitochondria-targeted antioxidants such as lipoic acid may be an effective strategy for reducing or preventing chronic oxidant-induced RPE degeneration in vivo from a variety of sources, including cigarette smoke."

More signs that r-lipoic is potent cellular protection at the mitochondrial level.

Only Geronova Research r-lipoic acids offer (proprietary) formulation providing very high bioavailability and sustained release.