Monday, December 31, 2007

Happy New Year!

Hopefully you had a healthy and prosperous 2007, and I wish you all an awesome 2008.

Here at Relentless Improvement I am looking forward to keeping you happy with industry leading quality documentation, high order fill rate and the widest selection of unique and effective supplements.

As always, I have some surprises in store for 2008 that will wow you (my customer) and stun the competition.

Thank you for your trust and support. With your continued business in 2008, we will keep reinventing the nutritional supplements business for the better!

Kind Regards,
Pete Hitesman - Owner
Relentless Improvement LLC
Livermore, CA

Thursday, December 20, 2007

Controlled Release Lipoic Acid - No Evidence for Efficacy

(1/14/2008: Note that the CRLA referred to in this paper are NOT Geronova's natural sustained release lipoics such as R-PLUS, Mito GOLD and R-PLUS with CoQ10.)

Brand new research released from Geronova Research, and associates, examines the science behind controlled release lipoic acid ("CRLA") and finds no evidence of benefits, safety or efficacy.

"The case against controlled release lipoic acid: A pharmacokinetic-mechanistic argument (part 1)"

Geronova and associates position is that CRLA proponent's marketing materials "fail to demonstrate superiority of CRLA" and that "It is important to distinguish marketing literature from science".

The Geronova paper clearly documents, with referenced research that "it is evident that rapid uptake and clearance of LA (Lipoic Acid) from the plasma is a beneficial attribute, not a shortcoming".

"All PK (pharmacokinetic) studies over the last 57 years provide irrefutable evidence that QRLA (quick release lipoic acid) is safe and efficacious. Recent attempts to market CRLA as a superior form of LA are without technical merit."

The new research paper was authored by:

David Carlson: Geronova director of R&D, specializing in R-lipoic and R-dihydrolipoic laboratory and industrial research.

Dr. Anthony Smith Ph.D: Linus Pauling Institute, author of multiple published, peer reviewed lipoic papers.

Dr. Heinz Ulrich, M.D.: Considered one of the worlds leading experts on lipoic acid and its use in clinical medicine. Dr. Ulrich has 44 patents and 15 peer reviewed articles on lipoic acid.

There is a ton of excellent information in this new paper, it will be worth your while to dig in. Those with a less technical interest can simply rest assured that Geronova Research r-lipoic acid supplements are the worlds best documented products, carefully researched and formulated for maximum possible benefits.

Your purchase of Geronova lipoic acid supplements supports continued groundbreaking research. I say, support those that support you! Want to chat about it? Discuss at the Relentless Improvement lipoic acid forum.

Tuesday, December 18, 2007

R-Lipoic Acid Pharmacokinetics in Humans.

Remember my previous blog post with pictures from Aug 9th about participating in a R-lipoic pk study at Geronova? Well the results are now published. Here is the PDF of the Human R-Lipoic Pharmacokinetic Study. (Also available on PubMed at this link: PK Study)

It is important to note this paper is co-authored by the "father" of modern lipoic and antioxidant research, Dr. Lester Packer - Dept of Pharmacology and Pharmaceutical Sciences, University of S. California and by Dr. Anthony R Smith of the Linus Pauling Institute, an expert in the use of RLA for vascular disease and author of seven peer reviewed papers.


Unstabilized (pure) r-lipoic (as found in most r-lipoic supplements) barely registered plasma levels above baseline(!), and "is not suitable for use in pharmaceutical or nutraceutical supplements".

Geronova's NaRLA provides a quick, high plasma peak. Much more so than than an unstabilized r-lipoic (anything other than manufactured by Geronova) or an alpha-lipoic acid. This is a good thing and thought to trigger the metabolic switches the same as exercise does.

Lipoic Acid is now being considered much more as a "stressor" (stimulation of Phase II and antioxidant response elements, not "stress" like emotional stress) than as an antioxidant. Provoking this cellular stressing is thought to offer anti-aging benefits.

"RESULTS: As anticipated from the preliminary study, NaRLA is less prone to polymerization, completely soluble in water, and displays significantly higher Cmax and AUC values and decreased time to maximum concentration (Tmax) and T1/2 values than RLA or rac-LA."

NaRLA is used in the formulation of Geronova's:

K-RALA (100 mg capsules) and K-RALA 300 mg capsules.
R-PLUS Curcumin
R-PLUS N-Acetyl-Cysteine

In case you were wondering, Geronova natural sustained release lipoic acid products work synergistically and with a somewhat different mechanism than the quick release products above. The natural sustained release products are:

R-PLUS and R-PLUS 120 count

The researcher's current opinion (when I asked them) is that it is preferable to combine both a quick release r-lipoic with a natural sustained release product in your supplement regimen to achieve maximum benefits.

Your purchase of these products supports and enables the kind of research usually only done by pharmaceutical companies. Geronova is the world leader in lipoic technology.

Closing anecdote: I was subject number 6 in the pk study. Of note, my lipoic plasma peak (Cmax) was 2-3 times as high as the other participants. More testing is planned in 2008.

Oops, late edit: Want to discuss this post? Log in to the Relentless Improvement Lipoic Acid Forum!

Friday, December 07, 2007

EgCG Green Tea Colon Cancer Protection?

New EgCG study released today with intriguing findins:

"According to research reported at the Sixth International Conference on Frontiers in Cancer Prevention, sponsored by the American Association for Cancer Research, a standardized green tea polyphenol (EgCG) preparation (Polyphenon E) limits the growth of colorectal tumors in rats treated with a substance that causes the cancer."

EgCG has a multitude of exciting health benefits. No matter your age or situation, you need to take a pure EgCG green tea extract daily in my opinion. Check out my previous post here on EgCG.

"The researchers believe these findings will pave the way for clinical trials with green tea polyphenols in humans."

And I for one cannot wait to see the results!

Carnsine Eye Drops For Cataracts

Customer Feedback:

"Hi Pete

Just a note to let you how impressed I've been by the Carnosine Eye Drops which you supplied so quickly a few weeks ago. I only ordered them as an "add-on" having read a comment in your blog about how effective they'd been for an older dog. I can't believe the difference they'd made to my own dog's eyes. He is an 8 year old bullmastiff who has suffered with entropion since birth. He's been slowly developing cataracts in both eyes and has also previously caused damage to both of them via either debris or by simply walking into things!

I started by giving him one drop in each eye four times a day and within a week his eyes were clear, bright and shiny - I can't recall the last time they looked like that. I've now reduced the dose to a drop a.m. and again before bed and will continue that for the next month when he is due for a regular check-up - with any luck the vet will confirm that his cataracts have either reduced or been cleared completely. Thanks a million!

I'll definitely be shopping with you again!(I'm also passing on the info about the carnosine eye drops to my vets both here in Switzerland and also in the UK)


Pete comment: Wow, gotta love that feedback. Note of caution: it usually takes months of use to obtain the results you seek. While this was a fast, happy, result, I think the carnosine eye drop speed of action in this example was exceptional.

Wednesday, December 05, 2007

Phenibut - Ready to Relax?

Phenibut is an amazing material. Find yourself stressed out with a tough day? Case of nerves? Just a higher level of vigilance than you really want? Phenibut is your friend.

I prefer to use a low dose, 1 capsule usually is quite noticeable. This way, the tolerance effect that can occur with Phenibut after several weeks use may be reduced or avoided.

Phenibut is also unique and amazing in that is supports cognition as it lends mood support! Unlike benzodiazepines for example, that relax and dumb you down and kill short term memory, phenibut supports memory.

A so called "Smart-Supplement" and relaxing mood support, that is Phenibut. A mighty fine combination for those crazy days that require peak mental fitness and mood support. Try phenibut today and see what you think.

PS- no nasty addiction potential like that found in prescription drugs! Safe, effective and almost too good to be true.

Monday, December 03, 2007

Centrophenoxine In Stock. Resveratrol Double-Talk

Centrophenoxine must be kept cool or it will degrade over time. We always keep our entire stock refrigerated until ready for shipment to you. No other supplier I know of does this. Quality does matter if you seek real results.

Our new 300mg trans-resveratrol supplement is a hit. Our customers love it for its purity and cost-effectiveness per milligram of trans-resveratrol.

However, sadly, you as a careful consumer MUST carefully examine the labels of other products on the market. You are looking for milligrams of "trans-resveratrol".

Many weasel suppliers are trying to fool you by hiding the true resveratrol content in jibber jabber about "Red wine extract" or "proprietary extracts", or disclosing the actual trans resveratrol content as a percentage of the overall extract content (hoping you won't do the math). It may be legal, but that doesn't make it right.

It is a shameful game, played to fool and deceive you.

High quality, low-emodin trans-resveratrol is expensive. The front of the Relentless Improvement label is crystal clear in big, bold letters: "Polygonum Cuspidatum Extract, Providing 300mg trans Resveratrol".

The Relentless Improvement resveratrol Supplement Facts Panel is equally straighforward: "Amount per serving:
Polygonum cuspidatum extract: 307 mg * [standardized to 98% purity, providing 300 mg transresveratrol]."

No hiding the facts, no trying to fool you. I am proud of this product!

One supplier is selling a 325mg resveratrol product derived from 650mg total resveratrol. That is a 50% purity extract! A 50% purity extract is so chock-full of emodin, you will never leave the bathroom after taking it! (emodin is a powerful laxative)

Compare to a high-potency resveratrol extract such as from Relentless Improvement with an emodin content documented by HPLC testing to be so low it is less than 0.02% per capsule.

You must read your labels, you must be a careful shopper. Relentless Improvement will always strive to offer you the overall best supplement value in the world.

Special Limited-Time Quantity Discount Prices

I did some price adjusting to nearly all of the Relentless Improvement brand supplements. Added some new quantity discount levels, and adjusted existing levels.

Worth your while to check it out, the deeper discounts are compelling. Stock up now and save.

These discounts are for a limited time only, while existing supplies last. Grab 'em and growl!


Friday, November 30, 2007

Customer Feedback

"Thanks for all your help. I'm always impressed with not only the quality of the supplements but also the friendly and professional service you provide. Before I discovered your site, I'd ordered supplements from a few other companies in the past, and they never provided anything even remotely close to that level of service. Now I refer people to your site whenever they ask about the supplements I'm taking.


Monday, November 26, 2007


Piracetam in stock and shipping same day.

As usual, oxiracetam and aniracetam also available. Documented by USA based, FDA certified, analytical laboratory for purity, lack of heavy metals, and lack of yeast/mold/microbial contamination. If you choose to supplement with piracetam, wouldn't you be more confident if you saw an independent Certificate of Analysis?

Of course.

Relentless Improvement is your world-wide quality assured headquarters for piracetam for good reason.

  • Fast, same day shipping.
  • Professional, international service.
  • Secure and convenient ecommerce shopping.
  • Documented purity.
With your support, you can expect more interesting and unique products in 2008.

Monday, November 19, 2007

Relentless Improvement Carnosine Eye Drops and Pet Cataracts. Customer Comment


Just a quick note to thank you for a fabulous product. (The N-Acetyl
L-Carnosine Eye drops
) I researched for quite a while and through HSI
(Health Science Institute) in Baltimore, discovered the (carnosine) eye drops.

Although I use them on myself sporadically as a preventive measure, I
really got them for our fourteen year old dog who developed cataracts
and was unable to see clearly anymore. After literally a week of
usage (twice a day) I could actually see the clouds in her eyes
shrinking and watched her climb the steps again without tripping on
them because of a misstep from her clouded vision.

I have given your website with kudos to your product to everyone I
know who has vision problems themselves or who have pets with vision problems.

Again, thank you so much for giving us a solution to an otherwise
helpless situation.


Very nice email to start off the week with. Our Relentless Improvement Lubricating Eye Drops w/ 1% Acetyl-l-Carnosine are in stock and ship same day for orders received by 1 PM Pacific.


Tuesday, November 13, 2007

Mera Pharmaceuticals Astaxanthin Overstock Sale.

Wow, huge price saving on Mera Pharmaceuticals Astaxanthin products. The quantity discounts are compelling and make sense for you to stock up.

I made a mistake and accidentally over ordered so my loss is your gain. Pricing good only while supplies last.

AstaFactor Rejuvenating Formula with Astaxanthin 5 mg per serving.
AstaFactor Sport Formula 10mg Astaxanthin 10 mg per serving.

Grab it and growl!

Wednesday, November 07, 2007

Price Increases, Inflation.

Just got another email this morning from a raw materials supplier: "Prices are going up". What is going on? Well, cast your first glance at the US Federal Reserve and their policy of interest rate cuts at the drop of a hat.

What? you ask?

Interest rate cuts, and focus on a Wall Street bailout policy, the policy that the FED is currently embracing, is killing the value of the US dollar against nearly every single currency on the face of the planet. Just last night China said it was looking at diversifying it humongous currency reserves out of mainly US dollars, and into other currencies.

Oil, a commodity we all use in our lives is at record highs per barrel. Gold, a true store of value is hitting new multi-decade highs. The CRB commodity index composed of a variety of commodities we all use, is hitting record highs.

All of this feeds into higher prices for the US consumer. Inflation is here and growing, thanks to cost of raw materials going up up up.

The more the FED debases our currency by cutting interest rates, the worse it is going to get.

Bottom line? If you are in the US, expect even more inflation in goods and services. Higher prices.

Bottom line for Relentless Improvement customers? If you are buying from us in a currency other than the US Dollar, our products are on sale, and cheaper than they have ever been! If you are spending dollars though, sorry, blame the Federal Reserve and Treasury Department under Hank Paulson, we have had to adjust some prices and more adjustments are in the pipeline and on the way.

If your finances allow you to stock up, this is the time. Right now, it is looking like prices adjustments will be increasing in amount and frequency.

Know this as well: We will not compromise our core business philosophy of assured quality, fast shipping and responsive customer service. I am a firm believer in the old aphorism:

"The bitterness of poor quality remains long after the sweetness of low price has been forgotten."

In these inflationary times, you must question competitors pricing that seems too good to be true- what are they leaving out, not doing, that allows a low price? There is no free lunch, and plenty of businesses are willing to sacrifice quality for profit.


Tuesday, November 06, 2007

Customer Feedback. Sulbutiamine and Galantamine.


Just wanted to comment on the excellent products you supply. My orders were delivered very promptly and the quality is unparalleled. I'm getting particularly noticeable results with the sulbutiamine, even at just 200-400 mgs/day. About an hour after just one capsule it feels as though I've woken up from the best sleep of my life. Vigilance and antiasthenia are maintained for 9-12 hrs afterwards with no afternoon or evening slump.

I had tried your recommended 600 mg once daily dosage but that made me feel anxious, restless, and jittery, so I reduced the dosage and have been well-rewarded. Since I'm combining the sulbutiamine with low-dosage galantamine (ala donepezil and the airline pilots), I'm probably experiencing a synergistic effect that permits, even requires, lower dosages of each. Moreover, they further complement one another in that galantamine also stimulates nicotinic receptors and sulbutiamine modulates dopaminergic and glutaminergic transmission.

My mood has been sensational, and my memory, which was already above average, is becoming phenomenal (noticeably easier time remembering my pathology, virology, and pharmacology). I highly recommended this potent combo (8-16 mg galantamine with 200-600 mgs sulbutiamine daily). I will soon be incorporating piracetam into the mix, albeit titered to my specific needs.

Thanks again for excellent service and quality,

Pete note: No statements on this site have been evaluated by the FDA. These products are not intended to diagnose, treat, cure, or prevent any disease.

Monday, November 05, 2007

Customer Feedback

"Dear Pete,

Your service, professionalism, commitment to product purity, and product innovation has been impeccable and because of this you are my exclusive supplement provider. I wish you continued success and want you to know that you have a customer for life.

Best Regards,

Thursday, November 01, 2007

"Aging Therapeutics Initiative" - Another Front in the War Against the Disease of Human Aging

Copied below is the text of press release dated October 30, 2007. This is intriguing stuff and worthy of your attention and support.


OCTOBER 30, 2007 - DUBLIN, CA - Author Dan Baker published one of the first novels on the topic of gene-based aging reversal in 2007. FOREVER AND EVER was developed with an eminent molecular biologist and featured aging reversal technology so accurate and plausible it ignited a fierce debate in the biotech community, and prompted calls for a privately funded biotech research effort to defeat human aging.

In the novel, biotech researchers team up with a billionaire to develop a revolutionary gene-based stem cell treatment that reverses aging. Freed from corporate and academic constraints, the scientists leap decades ahead in their research.

Mr. Baker’s book prompted University of Chicago longevity researcher, Dr. Leonid Gavrilov, to comment: “We will hear about this book soon from many people, leading to a loud public demand to start a serious biotech war on aging.” Dr. Stanley Shostak, a retired stem cell biologist, lauded the book’s scientific accuracy. “The most important feature of the novel is that Baker got the science right. He understands genomics, bio-informatics, and stem-cell therapy.”

“The small group of visionaries in this field have asked me to propose a privately-funded biotechnology research effort similar to that in my book. I believe this could deliver effective gene-based anti-aging therapeutics within the lifespan of the baby boomer generation,” Baker said. “We decided to call it the AGING THERAPEUTICS INITIATIVE.”

THE AGING THERAPEUTICS INITIATIVE will be the largest privately funded scientific effort in history. Princeton Professor Lee M. Silver said, “The ability to overcome the aging process and to achieve immortality will be the most significant medical breakthrough that will ever be made.”

Mr. Baker is mounting an effort to bring his book and the AGING THERAPEUTICS INITIATIVE to the attention of the world’s elite for private investment. “My book and the movie adaptation will popularize the idea of gene-based aging therapeutics. Once you popularize an idea, like Walt Disney did for space exploration, interest and funding usually follow, making it all possible,” Baker said.

Dr. Michael Fossel agrees. “What Mr. Baker is proposing -- a highly focused, privately-funded research effort to prevent, mitigate, or reverse human aging -- is plausible and viable. The baby boomers may become the first generation to be healthy well into their second century, if research is dramatically accelerated.”

“The AGING THERAPEUTICS INITIATIVE will identify, integrate, and fund key driver technologies including stem cell therapy, gene therapy, tissue engineering, artificial organs, regenerative medicine, and proteomics,” Baker said. “Cost will probably exceed ten billion dollars and development time will be in the twenty to thirty-year range.”

Dan Bakers book, FOREVER and EVER is the first fiction title on the topic of gene-based aging reversal and engineered human immortality. FOREVER and EVER is an incredible read, and I promise that you will come away at the end with an entirely new view on conquering human aging and lengthening healthy lifespans. Buy a copy today and see what the buzz is about.

You will also enjoy this YouTube video short entitled "The Immortalists" featuring Dan Baker, Ray Kurtzweil, Dr. Michael Fossel and others.


Monday, October 29, 2007

Relentless Improvement News Update. 2007 Recap, Thoughts for 2008

Time flies when you are busy, and November is about to be upon us. Given that 2007 is nearly over, I wanted to update you on Relentless Improvement's ability to serve you today and in the future.

You are seeking: 1. Availability 2. Unique supplements 3. Highest quality 4. Intelligent dosing per capsule 5. Fast shipping and 6. Simple, dependable and secure ecommerce platform.

And we delivered:

We introduced eight (!) new Relentless Improvement brand products in 2007. Each targeting a unique niche market.

1. Ultra high potency and quality EgCG Green Tea Extract. 357 mg EgCG per capsule derived from a unique chloroform-free extraction method.

2. Low emodin, 98% Resveratrol Extract. A huge 300mg per capsule for those seeking the high dose resveratrol lifestyle.

3. Convenient high-dose Strontium Citrate capsules offering 340 mg elemental strontium per capsule. Combined with k2, Strontium Citrate is the ultimate in bone building support.

4. Cost effective Vitamin K2 Menatetrenone. A full 15 mg per capsule, the dose shown in most studies to offer the highest level of bone building support. K2 Menatetrenone is best used in combination with Strontium Citrate.

5. Galantamine in a cost effective, easy dosing 8 mg scored tablet.

6. Lithium Orotate for life extension and mood support. 5 mg elemental Lithium Orotate per vegi-capsule.

7. Iodine/Iodide High Potency supplement. Compare to Iodoral. Glazed, enteric coated vegi-tablets prevent stomach upset and bad taste on the tongue from this iodine supplement.

8. Picamilon in a perfectly dosed 100 mg capsule. Picamilon has different effects in small doses than it does in larger doses.

We provided you a 100% fill rate on Relentless Improvement brand products. Do you hate backorders? You will love Relentless Improvement.

We always publicly document the quality of our finished products. Certificates of Analysis by well respected, FDA credentialed analytical laboratories are posted to our site shortly after product introduction. The CoA's are tied by lot number to the actual product we ship to you. Our competitors still refuse to follow our leadership. Why?

Simply put, an independent CoA by a credentialed laboratory is your ultimate assurance of quality, purity and claimed label content. Why would you accept less?

Smart, interesting, dosing of products: We carefully study the latest research when formulating a new Relentless Improvement product. Our intention is to offer you a dose and purity per capsule that allows you to conveniently, safely and cost effectively reach your supplementation goals.

We ship fast. We ship on Saturday. We ship same day for orders received before 1 PM pacific time. You want instant gratification? You got it.

Ecommerce is no game, and doing it well is no easy task. Our customers are provided with online ordering that is 100% up and available. Offering real time international shipping rates based on order size, ship to location and method. We are hosted on the most secure servers available. You can view your order process in the currency of your choice.

We are the clear choice for international customers. Especially with the US dollar being turned into confetti by our Federal Reserve. The weakness of the US dollar is allowing you to source our high-quality products at deep discounts.

We are international shipping specialists, and your orders usually pass your customs with no problems. Many suppliers are blacklisted by customs officials due to prior customs fraud (false invoices, etc). Relentless Improvement is in good standing with all customs authorities.

2007 was another year of huge growth, and truth be told, my single biggest challenge is scaling up all of our processes to keep up. A good problem to have. Relentless Improvement has certainly earned the world-wide reputation as a trusted source for high-quality supplements.

Of note, we came under repeated attack in several online forums from a person soon unmasked as a competitor hiding behind false online identities, even impersonating a doctor! Documentation of the poster's past subterfuge is found when Googling their screen name. Chronicles of their deception go back many years: Unique Nutrition for example (email me if you want more links).

2008 is a year you can look forward to. More new, unique products. Web site refinements. And more of the same great service that you have become accustomed to. With your continued orders we will continue to grow and serve your needs.

Thanks for your trust and support.

Pete Hitesman

Sunday, October 28, 2007

Customer Comments

"Holy hell your order system is a total nightmare!"

"Every time I place an order, I pull my hair out screaming because your system is such a bad hack, buggy, and poorly designed. It never remembers my password, and so i always have to order as a new customer. Checking "This is my preferred billing address" does then later give me a chance to type in a preferred shipping address. Failure. I always have to remember to uncheck that little "Send me spam" box, a.k.a. your mailings or whatever. That's so cheap. Instead, the better web sites have this default to unchecked. And then, after filling in all my info there's no "checkout" button, I need to hit other buttons before the checkout button finally comes out from hiding.


I bet we won't be seeing this letter on your site or in your blog. ;-)"

Pete comment: This was likely the most acidic customer email I have ever received. I can say that ad blocking software will interfere with full functionality of our shopping cart. Be sure you "whitelist" and Also, cookies must be enabled for many features to work.

Any personal information you enter on our site is never sold, rented or given to marketers. We don't share our customer list. Permanent opting out of our periodic email (approx once per month) is achieved either in your customer profile, or via an instant "unsubscribe" link in every mailing we send.

I hate spam, I receive on average about 500 daily, but I do appreciate occasional, brief, communication that provides value (new products, items on sale). Reaching out to a customer is always a balancing act of providing value vs unwanted intrusion. There are no perfect answers.

Well, GMail is a good answer :-) They have a superb spam filter so I never see those 500 daily spams! (My MX Server points to GMail).


Wednesday, October 17, 2007

Galantamine 8 mg Scored Vegi-Tablets Now in Stock

Our new Relentless Improvement brand Galantamine offers easy adjustment of dosing as we have introduced a new scored tablet. Simply and easily break our 8 mg tablt in half to obtain your 4 mg starting dose.

Galantamine can create some gastrointestinal upset and needs to be introduced in a low dose to help avoid this. 4 mg is the generally accepted dose for the first few weeks.

If desired, for greater effects, this 4 mg Galantamine dose can be adjusted upwards to 8 mg (1 tablet in stead of 1/2 tablet).

The new tablet formulation features Vegi-Tabs with a pharmaceutical glaze.

Try a bottle of Galantamine today, or stock up and enjoy our usual automatic quantity discounts (easily earned at only 2 and 3 bottles).

Tuesday, October 09, 2007

R-Lipoic Acid with N-Acetyl Cysteine (NAC)

More good news on the research front regarding R-Lipoic Acid and NAC (N-Acetyl-Cysteine). This Lipoic Acid/NAC study on PUBMED informs you that:

"...the antioxidants, lipoic acid (1 mM) and/or N-acetyl cysteine (100 muM) exerted a protective effect as evidenced by decreases in oxidative stress and apoptotic markers."


"...antioxidant therapies based on lipoic acid and N-acetyl cysteine supplementation may be promising."

As you know, Geronova Research offers a very unique R-Lipoic Acid / NAC combination product. As with all of their quick-release lipoics, R-PLUS NAC uses the latest NA-Rala form of r-lipoic acid which provides for excellent bioavailability and meaningful plasma levels.

If you are not using Geronova brand lipoics, you are not using the most advanced lipoics in the world. I wouldn't use any other supplier.


Thursday, October 04, 2007

Customer Feedback


Your company is a breath of fresh air! I had ran out of Nootropil (piracetam) about 3 weeks ago and ordered from another company online that was totally out of it. Never got it. Order from you company Friday night. Received Tuesday, just in time for our brand new hi tech startups' company kickoff, and several people, including myself commited to using the best supplements, such as these, to ensure our continued success. YOU ALL CAME THROUGH FOR US!!

Thank you!

Thank you for your trust and support. Feedback like this is what keeps us on our toes.

Tuesday, October 02, 2007

Piracetam- Documented Quality Is a Must

Piracetam, documented for your safety, is currently in stock. We ship same day for orders in by 1 PM and provide tracking numbers automatically by email upon shipment.

Fast, easy, dependable, and pure. Unlike any other supplier in the world, all Relentless Improvement brand products are 100% documented for claimed label contents.

Our testing labs are the best and most respected in the US. Certificates of Analysis by FDA certified analytical laboratories are your only proven assurance of quality.

If you seek a documented quality Piracetam, we are here to help you.

High Quality, Low Emodin Resveratrol

Relentless Improvement high-purity low emodin Resveratrol is officially a hit. The feedback is universally positive, people love the effects.

I continue to enjoy using it daily as part of a high-dose Resveratrol lifestyle (along with other polyphenols such as a high-purity EgCG Extract). If you previously used a low-purity resveratrol and experienced the gastrointestinal effects (gas, bloating, laxative effect) then you must try our product.

Zero laxative, gas or bloating effect.
Sense of energy.
Sense of greater endurance.
Cognitive benefits.
Anecdotal reports of slow but steady weight loss.

As with all of our products, our Resveratrol is fully documented. Third party analytical laboratory Certificates of Analysis are your only real assurance of quality and purity.

Try Relentless Improvement Resveratrol for six months and see for yourself.


Monday, October 01, 2007

Anti-Aging Novel: Forever and Ever

I just finished the new novel by Dan Baker, Forever and Ever. If the idea of curing aging or immortality interests you at all, it is a must read.

I couldn't wait to start reading, and once I began I could not put the book down. From biotechnologies such as gene therapy to stem cell organs and designer proteins, this is an amazing vision of what our future could look like.

Dan Baker also painted a vivid picture of the challenges and benefits that will present themselves with the discovery of aging treatments.

This is the perfect companion book to Aubrey de Grey and Michael Rae's new book Ending Aging: The Rejuvenation Breakthroughs That Could Reverse Human Aging in Our Lifetime

Buy and read both of these fine books, you will not be disappointed.


Saturday, September 29, 2007

Customer Feedback

"Hi Pete,

I just wanted to write and say thank you, once again. The (thank-you) card you
included with my order was a pleasant surprise. Service is quick,
ordering is easy and delivery is fast. Relentless Improvement will
continue to have 100% of my business.

Thanks again Pete. I wish you all the best in business and in life.

Your Customer"

Thank YOU sir!

Friday, September 28, 2007

Special Sale Pricing- Grab it while it lasts.

The special deals are in the quantity discounts on the product page bottom. Three or more earns you significant savings. Overstocked- my loss, is your gain. Sale pricing will end without notice once overstock is resolved. Buy today to avoid regret.

AOR Prostaphil-2
AOR Panthenine
AOR Total E Max
Mera Pharma Salmon Essentials w/Astaxanthin
LEF Acetyl-L-Carnitine Arginate

Happy Friday!

Wednesday, September 26, 2007

Green Tea Boosts Production of Detox Enzymes, Rendering Cancerous Chemicals Harmless

Ha, how's that for a headline? Provocative eh?

But this is no BS marketing hype. You must read this EgCG article:

"Concentrated chemicals derived from green tea dramatically boosted production of a group of key detoxification enzymes in people with low levels of these beneficial proteins, according to researchers at Arizona Cancer Center.

These findings, published in the August issue of Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research, suggest that a green tea concentrate might help some people strengthen their metabolic defense against toxins capable of causing cancer. "

"These pills contain(ed) epigallocatechin gallate (EGCG), a catechin known for its potent antioxidant activity, and are currently being tested against a variety of cancers in clinical trials."

You should be using EgCG daily. I do, and have bumped up my dose to 3 capsules. At these mg levels, you MUST use a documented pure material.

Only Relentless Improvement offers a documented, 357 mg EgCG per capsule, chloroform-free extraction product.

This is not a material where you will benefit by buying the cheapest, low mg, grocery store quality product (with the risk of residual solvents).

The Relentless Improvement brand documented quality product is available at this link: EgCG Green Tea Extract.


Monday, September 24, 2007

Awesome Customers, Great Music

Dealing with the public can frequently be challenging. You know what I mean :-)

But I am ever appreciative of the nice people in the world. Thank you Michael for the great music.

If you enjoy some relaxing, funky, wine drinking with a loved one R&B check out Lisa Shaw "Cherry" and blue six "aquarian angel" CD's.

Mighty good stuff and a fine way to relax your day and put a pep in your step!


International Customers... ATTENTION!

With the U.S. dollar at an all time low against the Euro and a 31 year low against the Canadian dollar, the purchasing power of international online shoppers is the best it has ever been.

Order now, reap the benefits. As you know, currency exchange rates are always fluctuating.

Relentless Improvement is an international shipping specialist and ships to all countries (except Iceland). Some supplement companies are "blacklisted" by customs because of past invoicing fraud. Not Relentless Improvement- it is the rare exception that any of our orders are rejected by a local customs authority.

Order with confidence from the most trusted name in supplements in the world. Documented quality, unique products, fast order fill. Your one-stop shop for high quality supplements.

Please read our Simple Shipping Policy for all the facts. Do not contact us for shipping charges, instead use the shopping cart to instantly determine your shipping charges in real-time.

No more waiting days for someone to contact you regarding shipping costs.


Iodine Supplement - New!

Check out the new Relentless Improvement Iodine Supplement, like Iodoral, but at a better price point.

Same formulation, same doses of Iodine (5 mg) and Iodide (as potassium salt 7.5mg), but the Relentless Improvement Iodine/Iodide High Potency Complex is less than half the price.

Compare Relentless Improvement 180 count at $39.99 introductory pricing (as low as $31.99 per bottle when 3 bottles are purchased) to Iodoral at $25.99 for 90 count bottle.

The new Relentless Improvement brand Iodine/Iodide is a compelling value.

Forever And Ever. More Good Reading

Want to enjoy a great fiction book about the longevity topic? Take a look at "Forever And Ever" by Dan Barker.

In the publishers words:

"FOREVER and EVER is the first fiction title on the topic of gene-based aging reversal and engineered human immortality. Developed over a four-year period with eminent molecular biologists and bioinformatics experts in the San Francisco Bay Area, FOREVER and EVER is a fascinating journey through the unprecedented social dilemmas, intense international power struggles, and bizarre possibilities of unlimited life in a youthful state."

I just got my copy and can't wait to get started. Will post a review when I finish, but a quick page-through looks great.


Saturday, September 15, 2007

We're Back! Orders From Last Week Will Ship Monday :-)

We're Back! Orders From Last Week Will Ship Monday :-)

Thanks for your patience. Several nes blog posts to come early this week.


Saturday, September 08, 2007

Ending Aging with Aubrey DeGrey and Michael Rae

I just got my copy of "Ending Aging" by Aubrey DeGrey with Michael Rae from Amazon today. Couldn't wait to crack it open a read a few chapters. Very good stuff as you might imagine, and I can highly recommend it as must have reading for any serious anti-aging explorers.

Aubrey, as you know, is the spear point behind The Methuselah Foundation and MPrize (along with Dave Gobel). His SENS (Strategies for Engineered Negligible Senescence) is a plan for postponing of age related physical and cognitive decline.

My company, Relentless Improvement has been a steady contributor and sponsor of MPrize for several years. Purely for selfish reasons :-). I have no reservation in admitting a desire for a (very) long, healthy life.

I couldn't be more thrilled to see two of the most outspoken and enthusiastic anti-aging proponents collaborate on this project.

Buy a copy today. And kick in a donation to MPrize! Just click on the link that is always top-right on my blog.


Wednesday, September 05, 2007

Natural Products Association Product Testing

In the latest NPA newsletter (RI has always been a member) they have admirably decided to embrace product testing (at several points) in order to help weed out the bad manufacturers and scam suppliers.


Relentless Improvement was founded and grows on the philosophy that documented products are a good thing. RI brand products have always had public Certificates of Analysis (from well-respected FDA certified analytical laboratories) available for public view on our website.

We are unique in that our CoA's are based on finished product and tied to the specific lot number of the product that is currently shipping to you. This is the ultimate in product quality accountability, and I don't know of another company in the world that does this.

I use what I sell, and frankly, I now hate to ingest anything that I have not had tested!

We have had all manner of headaches created by our testing regimen. It is difficult, time-consuming and very expensive. But if you lead a supplement lifestyle, and hope to reap the benefits, you must use only documented products.

There are unfortunately suppliers whose only concern is leading the race to the bottom with unsubstantiated claims, unknown purity and unsecured websites. That is a race we have never desired to enter.

Thanks to your ongoing trust and support, Relentless Improvement will continue to lead from a position of full disclosure, transparency and innovation. What other way is there?

Relentless Improvement Will be Closed Sept 10-14

RI shipping and order dept will be closed from Monday September 10 through Sunday September 16th. During this time orders may be placed as usual on for shipment upon our return on Monday September 17.

Place your order today to avoid any shipment delays!


Tuesday, August 21, 2007

NKO Neptune Krill Oil Added

You asked for it, you got it. NKO Neptune Krill Oil 60 capsules, 500 mg. Vitamin Research brand.

Thursday, August 09, 2007

Donating my Blood for Science. R-Lipoic PK Study.

I spent several hours yesterday afternoon helping science. Geronova is conducting another PK (pharmacokinetic) study of lipoic acid, and I volunteered to be a test subject.

When you purchase lipoic acid from Relentless Improvement, you are supporting the groundbreaking scientific research and development that Geronova does.

Dr. Anthony Smith, analytical chemist and biochemist is consulting with Geronova on this project. Dr. Smith is a lipoic acid specialist and has co-authored several papers with Dr. Tory Hagen.

Those with a scientific interest can read his published research on PUBMED at these links:

Vascular endothelial dysfunction in aging: loss of Akt-dependent endothelial nitric oxide synthase phosphorylation and partial restoration by (R)-alpha-lipoic acid.

Lipoic acid as a potential therapy for chronic diseases associated with oxidative stress.

Age-related changes in endothelial nitric oxide synthase phosphorylation and nitric oxide dependent vasodilation.

Plasma membrane-associated endothelial nitric oxide synthase and activity in aging rat aortic vascular endothelia markedly decline with age.

Vitamin C matters: increased oxidative stress in cultured human aortic endothelial cells without supplemental ascorbic acid.

Enjoy the pics (which you can click and view full size versions)...

Sarah Fischer, Geronova's Laboratory Coordinator and Licensed Phlebotomist, and me looking around in Lab 1 (upstairs).

Sarah Fischer gets the catheter in place and draws the first sample.

Sarah using the Glucometer to check blood glucose levels.

First page of the consent form to participate in the study.

David Carlson, Geronova Director of Research and Development, watches as Sarah spins down my blood samples in the centrifuge.

Dr. Anthony Smith prepares an HPLC analysis of my blood samples in downstairs laboratory 2.

Dr. Smith and David Carlson discuss test results.

With your support, Relentless Improvement documented quality supplements will continue raise the bar for quality and integrity.

Friday, July 27, 2007

My Supplement Regimen

I thought I would update readers on my current regimen. As the owner of a high quality supplements business, I try to keep up with the latest breakthroughs and have my pick of products to use personally.

My current daily products include:

Ortho-Core (multi).
Relentless Improvement brand high purity/potency EgCG.
Relentless Improvement high purity/potency Resveratrol.
Geronova Research R-PLUS or Mito Gold or R-PLUS w/CoQ10.
Geronova Carnitine Plus
LEF Acetyl Carnitine Arginate

Depending on my moods and daily workload I might add Relentless Improvement brand high purity Phenibut or Relentless Improvement brand high purity Sulbutiamine.

At 46 yrs old, I want to forestall or even reverse as much age related damage as possible. I currently believe that Lipoic Acid, Acetyl-L-Carnitine, EgCG, Resveratrol are my best choices.

While I cannot advise you what products you should supplement with, you might consider the above as inspiration.

Regular use demands that you chose only documented purity products. Only Relentless Improvement offers you 3rd party certificates of analysis for every product we offer. Tied by lot number to the exact product that we ship to you. "Pharmaceutical Grade" claims by suppliers are worthless without documentation.



I have to report my experience so far with resveratrol. I love it. Since receiving the new Relentless Improvement resveratrol last week I started taking 4 capsules daily and increasing the past several days to 6 daily (all in one morning dose).

Effects? Energy. Stamina. Sense of well being.

Ill effects? None. No gastrointestinal effects at all. Low emodin content is key to not only tolerating, but enjoying a high dose resveratrol regimen.

Several studies seem to indicate that an effective dose in humans may be as much (or more than) as 500 mg per 50 lbs of body weight. As the science is continually evolving, this may change.

While a high dose, high purity resveratrol lifestyle is not inexpensive, the science so far is very intriguing. Resveratrol may be closest material we have yet for healthy life-extension in a pill.


Monday, July 09, 2007

Elixir of Youth, In A Pill? Resveratrol May Be It.

Nice article in the New York Times about David Sinclair and Sirtris Pharmaceuticals work with High Potency Resveratrol:

"a molecular compound called resveratrol, found in red wine and other plant products, extends the life span of mice by as much as 24 percent and the life span of other animals, such as flies and fish, by as much as 59 percent."

"Resveratrol may therefore be mimicking caloric restriction without an arduous diet that few people can maintain for very long."

"In any case, he says, mice have consumed as much as 400 milligrams of resveratrol per kilogram of body weight without ill effect. On the contrary, the rodents became sleek, slim and powerfully athletic. (A human would have to drink 10,000 bottles of wine a day to consume the same quantity of resveratrol.)"

Most Polygonum cuspidatum extract supplements, which provide resveratrol, currently on the market are very low dose and contain huge amounts of an impurity called "emodin" which causes a pronounced laxative and flatulence effect. Ugh.

Relentless Improvement brand Resveratrol is based on a very pure 98% extract, and offers 300mg per capsule, with very low emodin content.

Relentless Improvement is the leader in high quality supplements worldwide.


Thursday, July 05, 2007

Diabetes and Lipoic Acid

The latest issue of New Scientist reports in this story that "One of the nasty tricks that diabetes has up its sleeve is the ability to carry on harming people long after they have got the level of glucose in their blood under control. Now researchers think they may be able to stop this, using cheap available drugs"

"The clue came from lab experiments in which they took damaged cells that had been previously exposed to high levels of glucose, and showed that the reactive molecules could be neutralized by exposing the cells to antioxidants such as alpha-lipoic acid (Diabetologia, DOI: 10.1007/s00125-007-0684-2)."

Relentless Improvement high-quality supplements offers the most diverse and potent selection of lipoic acid supplements anywhere in the world. These are in stock, and ship same day. You owe it to yourself to use the the highest quality quality lipoics from the only North American manufacturer of r-lipoic acid.

Friday, June 22, 2007

FDA Issues New Safety Rules for Vitamins

Good news for consumers, FDA rules that supplement suppliers must begin having all their products tested. has been way out in front on this serious issue, voluntarily testing all of our products from day one. In fact, I don't know of any other business that provides their customers an independent FDA certified laboratory analysis of their products, with each CoA linked to the specific product's lot number (!).

It is time-consuming, expensive, a huge headache with some products, and absolutely necessary.

If you see any company claiming on their label "pharmaceutical grade" you must DEMAND to see proof of this label claim via third party, FDA certified, laboratory analysis. Otherwise they are committing fraud against YOU, their customer.

From this story:

"FDA Issues New Safety Rules for Vitamins

By KEVIN FREKING, Associated Press Writer

For the first time, manufacturers of vitamins, herbal pills and other dietary supplements will have to test all of their products' ingredients, the Food and Drug Administration announced Friday.

The agency is phasing in the new rule, which is designed to address concerns that existing federal regulations allowed supplements onto the market that were contaminated or didn't contain the dietary ingredients claimed on the label.

Last year, the agency found that some supplements contained undeclared active ingredients used in prescription drugs for erectile dysfunction. In the past, regulators found supplements that didn't contain the levels of Vitamin C or Vitamin A that were claimed.

If, upon inspection, the FDA finds that supplements do not contain the ingredients they claim to contain, the agency would consider the products adulterated or misbranded. In minor cases, the agency could ask the manufacturer to remove the ingredient or revise its label. In more serious cases, it could seize the product, file a lawsuit or even seek criminal charges.

Dietary supplements - pills, liquids or other products people take to improve their diets - are a $22 billion industry.

Most companies already test their raw ingredients once they come into the plant, said Steve Mister, president and CEO for the Council for Responsible Nutrition, a trade association representing about 65 manufacturers.

"This raises the bar so that all have to comply," Mister said.

The new rule goes into effect Aug. 24 and will have a three-year phase-in that gives smaller manufacturers more time to comply. However, even the largest of the manufactures won't have to comply until June 2008.

The rule applies to all domestic and foreign companies that manufacture, package and label supplements for sale in the U.S. It requires them to analyze the identity, purity and strength of all the ingredients that go into their products before they are distributed.

It also includes requirements for record keeping and handling consumer complaints.

Dr. Sidney Wolfe, who has testified before Congress on problems with dietary supplements, said the new rule does not ease his concern that unsafe supplements are too easy to bring to market.

"You still don't have to show the product is safe. You don't have to prove it works," said Wolfe, director of Public Citizen's Health Research Group.

Congress limited the Food and Drug Administration's oversight of vitamins and other dietary supplements in 1994. The new rule is a product of that law, meaning that the rule took nearly 13 years to develop.

Under the old regulations, supplements were governed by the same rules that applied to producing foods, such as cans of soup.

"The final rule will help ensure that dietary supplements are manufactured with controls that result in a consistent product free of contamination, with accurate labeling," said Dr. Robert E. Brackett, director of FDA's Center for Food Safety and Applied Nutrition. "

Wednesday, June 13, 2007

Chloroform-Free EGCG Green Tea Extract. Now in Stock

Trust Relentless Improvement to come out with a better Green Tea Extract. Now in stock, Chloroform-free EgCG Green Tea Extract.

A massive 357 mg of EgCG per capsule. A huge 602 mg of total catechins per capsule. Other green tea extracts don't come close to this potency of EgCG because they use a less pure grade of Green Tea Extract.

Currently at introductory pricing.

Monday, June 04, 2007 Is New And Improved

Go check out Betterhumans new site right now. Simon has done a fine job creating a new look and feel. Content is better than ever. I like that I can visit and get all the latest news in one easy to read format. Betterhumans should be on the daily visit list for everyone reading this blog.

"Betterhumans is a community of forward thinkers dedicated to discussing, celebrating and creating the future. Through the facilitation and aggregation of informative and provocative content and the creation and application of enabling communications technology, we aim to get more people thinking about the future, inspire people into assuming a proactive and participatory role in its creation and build, lead and support an informed movement for positive change."

Good stuff and worthy of your Favorites Links List!

Friday, June 01, 2007

Do You Live Outside the USA? We Have a Sale for you.

International supplement customers, you should be rejoicing and pulling out your wallets.

As you know the trade weighted dollar value is hitting multi-year lows. What this means to you is that your AUD, CAD, EUR, GBP, CHF, HKD, and NZD, for example, buys more in US dollar denominated products than it has in many years.

But that's not all: When you buy from Relentless Improvement you receive tremendous value for your money. We have always served our international customers better than nearly any other supplement supplier. How so?

1. Real-time, instant shipping cost quote in our shopping cart. So easy! No wasting your time exchanging emails and phone calls with a business in a differ time zone.

2. Fast order shipping (usually same day!).

3. Superb customer service. We answer emails quickly. During business hours, usually within 60 minutes.

4. Orders priced in your choice of currency. Less confusion! When shopping in our online store, simply choose to have the cart price the order in your desired currency.

5. Proven, documented quality. Third party, product Certificates of Analysis posted online for you to see whenever you want to. Tied to the lot number of the product that you receive. No other supplier offers this degree of quality assurance. Undocumented website and label claims are worthless, detailed public documentation is your only real proof. Demand it.

6. Professional ecommerce platform. Secure, safe, fast, easy, reliable. The online store is always up for you. Nobody runs a more professional ecommerce business than we do.

It all adds up to great value for International customers. Let us be your source for highest quality supplements.


Thursday, May 31, 2007

Exercise Proven (Again) to Reverse Aging

Buck Institute recent anti-aging study says:

"The vast majority of aging studies are done in worms, fruit flies and mice; this study was done in humans," said Melov. "It's particularly rewarding to be able to scientifically validate something practical that people can do now to improve their health and the quality of their lives, as well as knowing that they are doing something which is actually reversing aspects of the aging process."

1. Heathy diet
2. Exercise
3. High Quality Supplements

Your recipe for a long and healthy life.


Friday, May 25, 2007

American Analytical Chemistry Lab Information, Customer Feedback

A customer wrote to me concerned about a post he read on a website about one of the analytical testing labs I use. The post is apparently an attempt to somehow cast doubt on our product quality. Let me set the record straight:

1. AACL is a FDA inspected and credentialed laboratory. That is a fact.
2. Attempting to infer that the quality of our finished product could somehow be compromised by the choice of testing lab is absurd.

Relentless Improvement has shaken up supplement suppliers that only give lip service to quality. But I am shocked that we would come under attack by those unwilling to document their product quality (Isn't it crazy they would attack us for providing a higher-quality product?)

I have learned that the post purporting to present readers information about our testing lab is by an individual posing as a physician online. Not only is this poster a fraud (no medical license can be found when searching the state physician database) he is in reality associated with a competing business that sells supplements!

The Internet message boards are often populated by people hiding behind false identities with hidden agendas. As a careful consumer you must be aware all is not at it may first appear. That is the case here, disparaging posts by a competitor hiding behind their dark cloak of (perceived) anonymity.

I challenge you to shine the light of truth on these roaches. Call them out. And let them know how you feel about their slimy tactics by boycotting their businesses.

If anyone has concerns that I have not addressed, I am always available by telephone during business hours for further discussion.

Take care and have a good weekend.

Oh, I almost forgot. My customers comments to all this? Read below:

"Hi Pete,

Fair enough! As long as the lab is fully FDA certified, that is good enough for me. I've checked out your site, I've read your blog, and I am impressed. I can honestly say that this was the deciding factor when choosing to do business with your company. The other sites seem somewhat shady, while your site and manner of presentation is forth right, and educational to the customers. I appreciate the level of quality you strive for, and I appreciate your invitation to discuss the matter over the phone. Although that is not necessary, as your email addresses everything, the offer you provide to discuss the matter clearly shows that you give a damn.

I wish you continued success with your business Pete. I've had all my orders FAST, and I look forward to continue my patronage with your store!

Thanks again !!"

Monday, May 21, 2007

EGCG - Green Tea, More Good News (and New RI Product!)

The good news on EGCG Green tea Extract just keeps coming.

Tea 'healthier' drink than water

"They found clear evidence that drinking three to four cups of tea a day can cut the chances of having a heart attack.

Some studies suggested tea consumption protected against cancer, although this effect was less clear-cut.

Other health benefits seen included protection against tooth plaque and potentially tooth decay, plus bone strengthening.

Dr Ruxton said: "Drinking tea is actually better for you than drinking water. Water is essentially replacing fluid. Tea replaces fluids and contains antioxidants so it's got two things going for it."

News you already knew:
Green tea extract 'is cancer aid'
Green tea compound Alzheimer hope
Green tea 'may protect the heart'

The challenge for you, finding an ultra high-quality EGCG Green Tea Extract. Did you know most EGCG green tea supplements are produced using a chloroform extraction method? UGH! Not good because it leaves chloroform residues. is a few weeks away from introducing a certified chloroform free, ultra high-potency EGCG green tea extract product.

Stay tuned as we continue to lead the way to high quality, safer, more effective supplements and vitamins.

Friday, May 18, 2007

Lipoic Acid Explored As Anti-aging Compound

Some great news being released today. Tory Hagen (bio), a noted well-respected researcher was quoted in this article:

"Our studies have shown that mice supplemented with lipoic acid have a cognitive ability, behavior, and genetic expression of almost 100 detoxification and antioxidant genes that are comparable to that of young animals," Hagen said. "They aren't just living longer, they are living better – and that's the goal we're after."


"We never really expected such a surprising range of benefits from one compound," Hagen said. "This is really unprecedented, and we're pretty excited about it." is your lipoic specialist due to our close association with US lipoic manufacturer Geronova Research. We offer the most advanced lipoic products of any distributor in the world.

Combining Carnitine Plus (acetyl-l-carnitine and carnitine orotate) and lipoic acid supplements in your regimen is a proven anti-aging strategy.

Stay tuned, much more good news coming on lipoics!

Thursday, May 17, 2007

Carnosine Eye Drops- Customer Feedback

Email from a customer today regarding our carnosine eye drop:


I think you will be interested in the following:

A year ago, I had an eye exam. My ophthalmologist indicated that my left eye had weakened significantly and I had the beginning stages of cataract formation. I found the Russian research on the internet and discovered that you have the drops as a private label product. I have ordered various products from you over the past couple of years.

I was scheduled to go for a follow-up at six months but did not do that because I wanted a longer period of time to use the NAC drops to see if I could avoid IOL implants.

Incredible results - No cataract formation and my left eye has improved significantly. The Dr. was extremely surprised. Perhaps the NAC drops worked better because I am taking various anti-aging supplements. Of particular impact could be benfotamine and (a pyridoximine) product I have been using due to a pre-diabetic condition. I did not mention the NAC drops to the Dr. because they see this stuff as "snake oil". Obviously, I will continue to use your NAC drops.

Anon by request"

Carnosine eye drops
from Relentless Improvement are documented purity, sterility and potency.

Theralac Probiotic / Prebiotic - Professionally Recommended.

A high-quality, potent probiotic is esseential to good health. I have been convinced of this fact for years. The bugs colonizing your gut are vital to proper digestion and to obtain the nutriton form the foods that you eat.

Quotes below from a write-up on

"Probiotics will someday be recognized as "a new essential food group," predicts Gary Huffnagle, PhD, a professor of internal medicine at the University of Michigan Medical School and a prominent probiotics researcher. "I believe we'll eventually have research-based minimum daily requirements for probiotics," he says, "just as we do for many vitamins and minerals."


"A recent analysis by independent tester found that out of 13 products tested, only 8 delivered at least 1 billion live organisms per serving--a generally accepted minimum."

We offer the Theralac probiotic (which is mentioned in the story as a recommended product) as our only probiotic offering. In my opinion it is simply the very best.

Theralac's 20 billion CFU/capsule are guaranteed through expiration.

The makers of Theralac also offer Enzalase™ Enzyme Master Supplement. This is a smart addition to probiotic therapy.

Theralac and Enzalase are not sold in stores.

Wednesday, May 16, 2007

New Products: Picamilon, Strontium Citrate, K2 Menatetrenone

Now in stock:

Picamilon - Nootropic, cognitive enhancer. Stimulation/relaxation depending on dose. Cost effective 100 mg x 60 capsules. Easy open capsules allow you to adjust dose if you desire.
Strontium Citrate - Bone builder, osteoporosis support. High-dose 340 mg per capsule x 120 capsules.
Vitamin K2 Menatetrenone - Bone builder, osteoporosis support. High-dose 15 mg per capsule X 90 capsules

CoA's to be posted shortly. More interesting new products in the pipeline as Relentless Improvement vitamins and supplements takes tighter control over product quality.

Thanks as always for your trust and support!

Monday, May 07, 2007

Amazing- From China to Panama, a Trail of Poisoned Medicine

NY Times this weekend had an incredible story.

"Shipping records showed the contents to be 99.5 percent pure glycerin.

It would be months and many deaths later before that certification was discovered to be pure fiction."

"The mystery had been solved. The barrels labeled glycerin turned out to contain poison."

This on top of the wheat gluten being contaminated by melamine story. If you are still not convinced of the necessity of 3rd party testing, you never will be.

While I strive to keep Relentless Improvement vitamins and supplements price competitive, my first and foremost concern is quality. That is why ALL our RI brand products are certified by an FDA approved analytical lab.

It is your choice- do you invest in a documented quality product from Relentless Improvement? Or do you roll the dice with your health?


Thanks to Dave Jensen's great "Sham vs Wham" Health Insider blog for letting me know about this story.

Tuesday, May 01, 2007

DHA- Protect Your Brain From Alzheimer's?

Pleanty of evidence already out there on the benefits of eating oily fish and using Omega-3 Supplements. Another story out this week says:

"In Alzheimer's disease, lesions known as "plaques" and "tangles" form in the brain, due to the abnormal clumping of two proteins called beta-amyloid and tau. The mouse study found that a diet rich in the fatty acid DHA might interfere with this process"


"The researchers also discovered that DHA may confer its benefit by lowering levels of an enzyme needed to generate beta-amyloid."

I have always been a big believer in fish oils and offer several molecularly distilled products:

EPA/DHA w/Olive and Sesame Lignans
Nordic Naturals Ultimate Omega
Nordic Naturals EPA
Salmon Essentials with Astaxanthin (Mera Pharmaceuticals, one of my favorites)


Monday, April 30, 2007

FDA Draft Guidance Is Not A Concern

From the Natural Products Association, a supplement industry trade group:

"Association to Comment on FDA Guidance…The association has recently heard from members concerned about a draft “guidance” document from the Food and Drug Administration (FDA) on complementary and alternative medicine (CAM) that some are claiming will, among other things, classify all dietary supplements as drugs and curtail certain practices. As we stated in the April 16 edition of The Supplement, this is untrue. While the Natural Products Association recognizes that the guidance document itself does not affect the practices or products used in CAM, it does represent the FDA’s viewpoints about CAM, and in that regard, could be clearer. The association intends to file formal comments by the new submission deadline, May 29, 2007. Meanwhile, to assist members and others who have questions about the guidance, a new area is being created on the Natural Products Association’s Web site at

To reiterate what was previously communicated, a “guidance” document is by definition not legally binding and does not change or create laws or regulations. Guidances, like the one in question, are usually issued to help explain how a law or laws are applied. In this case, the guidance clarifies how products and practices used in CAM are regulated under different provisions or statutes depending on their intended use and claims. The deadline for sending comments to the FDA on the draft guidance document has been extended to May 29, and comments can be sent to the FDA’s comment area, or mailed to Division of Dockets Management (HFA-305), Food and Drug Administration, 5630 Fishers Ln, Room 1061, Rockville, MD 20853. Refer to Docket No. 2006D-0480. Whether finalized or not, the draft guidance will not change current laws and regulations, such as the Food Drug and Cosmetic Act, which the Dietary Supplement Health and Education Act amended. The Natural Products Association is preparing comments to the FDA and is monitoring this and any other drafts, and will keep you up to date on any relevant developments that may affect our industry."

Friday, April 27, 2007


Have I mentioned how much I like Phenibut? Relaxing, calming, providing a clarity of thought that is very noticible. Like xanax in many ways, but without the memory loss and sleepiness associated with benzodiazpines.

Phenibut is best used long term in lower doses so that tolerance does not build up. It is thought best to "cycle" phenibut use, after continued use, take a break for a week or two.

So nice to find both calming and nootropic effects in the same material. Available at the most trusted name in supplements.

Happy Friday!

Wednesday, April 25, 2007

Fraud In The Supplement Business?

I have been known to use a line when talking to customers, regarding the risks of undocumented products: "products mixed with boat paddles in blue plastic barrels in some body's garage". Well, in this mind-blowing story from MSNBC, I was only wrong about the color of the barrel:

"To mask the chemicals' taste, the affidavit alleges, Wheat and others mixed the active ingredients with water, blue raspberry Kool-Aid and sugar in 55-gallon drums in a rented storage unit in Duluth, Ga., ending up with a bluish liquid that one witness said looked like Windex."

This example is the exception and not the rule in the supplement business. However, I personally know of unethical business practices, downright fraudulent label claims and product contents consisting of only marketing hype and none of the claimed material.

Bottom line, you damn well better deal with a business of proven integrity, honesty and reliability. Full disclosure (no "proprietary formulations") and third party analytical testing must be foremost in your buying decision.

If you let price and hype be the determinants of your buying decision, you might well be sacrificing your health. Relentless Improvement has earned the reputation as the clear leader in proven purity supplements and nootropics. We will continue to lead as others fall by the wayside.

Caveat Emptor

Saturday, April 21, 2007

Waiters in 40 restaurants in 5 states stole diner's credit card info

Wow, I read this headline today and shook my head. Highlights of this CNN story:

• Waiters in 40 restaurants in 5 states stole diner's credit card information
• Ringleaders paid waiters $35 to $50 for information from each credit card
• Suspects then created high-quality counterfeit credit cards
• Credit card fraud ring operated from November 2005 until this week

Customers will sometimes discuss with me the use of their credit card for online purchases. And they are right to be concerned. I have heard some stories about other sites having terrible security!

Lets look at ecommerce ordering:

Once you place an online order, many small, unprofessional websites receive it via an email notification. This has your credit card info on it for anybody to see (or to be intercepted by a hacker or unauthorized user). These emails sit on unsecured computers at high risk of compromise by any existing (or future!) users.

The businesses then prints out these order emails for their shipping department. Then what happens to them? Where do they go? Do they go in the trash can to be fished out by the dumpster diving bad guys?

It is worthless for a site to advertise 128 bit encryption, while exposing your payment information to a variety of other compromises.

Relentless Improvement takes your security very seriously. Upon entering your order into our SSL protected shopping cart, your credit card information goes directly into an encrypted server, via a secure encrypted link. These servers are co-located in a high-security data center that also serves banks and credit card companies.

In our state of the art order management system only the last four digits of your credit card are visible to employees. Your information is never printed out, or exposed to hackers in unsafe emails.

Furthermore, all Relentless Improvement customer service computers are secured by PGP Whole Disk Encryption. In the remote event an unauthorised individual gained entry and attempted access, they would find it impossible as PGP encryption is considered by all experts to be impenetrable.

When buying from a company with nothing but cheap prices (and unknown quality), you can be assured they cannot afford (and could care less about) the protections necessary to prevent your identity theft.

Be a smart shopper and careful consumer. Now, more than ever, integrity matters.


Friday, April 20, 2007

Melamine Intentionally Added to Chinese Products?

ABC is reporting on the likelyhood that the terrible pet food poisoning may have have been the result of intentional "spiking" of the raw materials.

"Food and Drug Administration investigators say the Chinese companies may have spiked products with the chemical melamine so that they would appear, in tests, to have more value as protein products."

This is just a terrible, horrible story no matter how you look at it. And it once again reinforces my decision to have all Relentless Improvement branded products tested by a fully FDA accredited analytical lab. A third party Certificate of Analysis is your only assurance of purity, potency and proof of capsule contents.

HPLC testing (which is conducted on all RI products) will show a single spike for the active ingredient. Any other spikes better be an excipient such as a flow agent, otherwise it is indication of a contaminant.

Furthermore, our rigorous testing protocol even complies with California Prop 65 requirements, even though Relentless Improvement is not required to adhere to Prop 65 (due to our size). But we test as if we were. Proposition 65 was passed nearly 10 years ago by the voters in California and established California-only allowable levels of daily ingestion of four heavy metals.

Remember, the FDA does not require the testing of nutritional supplement finished products. I cringe when I see some companies claiming "Pharmaceutical Grade" on their labels, because I know they have never been subject to testing. There could be anything in those bottles.

As the leading USA nootropic supplier, we set a high standard that others can't even attempt to match.

Demand integrity when you purchase supplements.

Happy Weekend,

Wednesday, April 18, 2007

Enjoy High Quality Anti-Aging News at MPrize, Fight Aging! and Longevitymeme

Some of the very best, cutting edge, anti-aging discourse and news in the world is found on, and Invest some time to check out these superb sites and soak up the thought-provoking information and discussion.

What is MPrize all about? "A financial award offered to scientists who can demonstrate healthy life-extension in a mouse, it uses the tried and true ability of money, fame, and competition, to draw attention to the possibility of the near-term development of real anti-aging medicine."

MPrize is promoting research that will result in your improved quality of life and lengthened lifespan. Those are goals that appeal to me!

I urge you to contribute to MPrize. Why not add your investment for a better future for mankind? I did.


Tuesday, April 17, 2007

Growing To Serve You Better. Relentless Improvement To Offer More High Quality Supplements.

Relentless Improvement must have the best and most loyal bunch of customers in the world. For that, I thank you all.

And thanks to your repeat orders and ongoing support, there are good things happening. Many new Relentless Improvement brand products in the pipeline. We heard you loud and clear: integrity, reliability and trust matter to you. The next several weeks will see the introduction of 6-10 brand new, uniquely dosed and formulated, RI brand products.

We continue to provide you fast shipping, documented quality, and high value for your nutrition supplement dollar. And a reputation for unique products found nowhere else.

Many surprises in the works for 2007, and we will continue to lead the way as the premier supplier of high quality supplements and vitamins.


Saturday, April 14, 2007

My Top 5 Favorite Supplements

There are some basics, foundational supplements if you will, that I have found to be indispensable. When I travel, they always go into my suitcase. While I may add to this as I feel the need, these always seem be the foundation:

Stabilized, sustained-release RLipoic
Omega-3 Fish Oil

Also part of my regimen is our new, pharmaceutical grade Alpha-GPC (a documented minimum 323+mg active load), phenibut (as needed) and a high potency probiotic/prebiotic, Theralac.

So there you go. Always subject to change, but it never seems to change much :-)

You are of course different from me in your needs, but the basic supplement will benefit most people reading this blog.

Happy Weekend!

Thursday, April 05, 2007

Benfotiamine - Super Sale

This is a real deal, AOR high quality Benfotiamine is overstocked and on sale.

Benfotiamine is a powerful "late-phase" inhibitor of Advanced Glycation Endproduct (AGE) formation (so called AGE-breaker), acting through several mechanisms to reduce the irreversible nonenzymatic modification of the structure and function of bodily proteins by sugars, resulting in documented maintenance of the structure and function of retinal, nervous, glomerulal, and other tissues.

1 each and 3 or more pricing is below my cost! Now that is a great deal for you.


Vitamins and Supplements

Carnosine Eye Drops - Don't Fall For The Marketing Hype.

Let me point out some facts on Carnosine Eye Drops:
  • All the studies were conducted with the acetlyated form of carnosine (Acety-L-Carnosine). A company sells a version that is simple "l-carnosine" which has no science behind it.
  • Benzyl alcohol has decades of use, is proven very safe and does not cause stinging.
  • Any stinging, which in my experience is very, very rare, is caused by pH difference. Our carnosine eye drops pH is adjusted just right.
  • A new drop is using a preservative called Biopolynate, now I am worried about this because I don't think it has an established safety record like benzyl alcohol does.
  • Also- if this new drop has a pH above 7, then it cannot penetrate the cornea.
Another company claims that only a patented product can be effective, this is crazy! A molecule's beneficial action is not determined by it's patent status. Furthermore I have never found a US patent issued.

As always, we have to separate the facts from the marketing hype. The fact is, Relentless Improvement provides a proven purity, proven content carnosine eye drop. We are the only supplier to provide you a fully 3rd party analyzed product for your safety and peace of mind.

Now that is good news.


Carnosine Eye Drops