Sunday, September 29, 2013

Uterine Fibroids and EGCG (Green Tea Extract)

 Good news for women concerned about uterine fibroids. A new study on PubMed evaluates the efficacy and safety of green tea extract, specifically epigallocatechin gallate [EGCG] in a double-blinded, placebo-controlled randomized clinical trial. By the end of the study, fibroid size (volume) was reduced by 32.6% among women receiving the EGCG extract, while it increased 24.3% in the placebo group.

The women used 800 mg of green tea extract (EGCG) or a placebo, taken after meals, daily for 4 months. In the placebo group (n = 11), fibroid volume increased (24.3%) over the study period; however, patients randomized to green tea extract (n = 22, 800 mg/day) treatment showed significant reduction in total UF volume. In addition, EGCG treatment significantly reduced fibroid-specific symptom severity compared to the placebo group. Anemia also significantly improved in the EGCG treatment group (anemia can occur with fibroids). No adverse effects were observed in either group.

For those choosing to use an EGCG supplement, a critical consideration is to use a documented pharmaceutical grade green tea extract standardized to a high EgCG content, low in caffeine and NOT derived via a chloroform extraction process. Furthermore it is essential that any green tea supplement be tested for the existence of contaminating heavy metals. Relentless Improvement brand Green Tea EgCG Supplement meets all of these qualifications and carries a public Certificate of Analysis of purity, sterility and claimed EGCG content. 

EGCG shows promise as a safe and effective therapeutic agent for women with symptomatic UFs. Such a simple, inexpensive, and orally administered therapy can improve women's health globally.

Taking a green tea extract is not advisable for women who may be conceiving or are pregnant, due to increased risk of birth defects (see Concerns and Cautions).