Monday, June 22, 2009

Did You Know? R-PLUS Curcumin Features BCM-95

What is BCM-95 and who cares? you might ask...

""Six-month, Randomized, Placebo-Controlled, Double-Blind, Pilot Clinical Trial of Curcumin in Patients with Alzheimer Disease," Baum L, Wai Kei Lam C, et al, Journal of Clinical Psychopharmacology, 2008; 28: 110-13. (Address: Larry Baum, Dept of Medicine and Therapeutics, The Chinese University of Hong Kong, Shatin, Hong Kong. E-mail: lwbaum@cuhk.edu.hk ).

Summary: In a 6-month, randomized, double-blind, placebo-controlled pilot clinical trial involving 22 patients with Alzheimer's disease, supplementation with a particular curcumin supplement (BCM-95 capsules) was found to have significantly greater bioavailability, as compared to conventional curcumin powder, suggesting it may provide better clinical benefits. Subjects (aged 50 years of age or older) with progressive decline in memory or cognitive function, diagnosed with probable or possible Alzheimer's disease were given: 1.0 g/d curcumin, 4.0 g/d curcumin, or placebo, taken after a meal (capsules) or mixed with food (powder), for a period of 6 months. Supplementation with curcumin was found to increase levels of serum Abeta, possibly reflecting the ability of curcumin to disaggregate Abeta deposits in the brain. Significant increases in vitamin E were found as well, with greater increases found among subjects who took the BCM-95 capsulses. In addition, BMC-95 was absorbed 7.8 times more than conventional curcumin; this bioavailability may confer greater clinical benefits. The authors recommend that BCM-95 be used in future clinical trials. A larger trial of a longer duration is warranted."

Geronova Research R-PLUS Curcumin uses the highly bioavailable BCM-95 material. Oh and don't forget, it is on sale now.

Quality matters!
Pete

Tuesday, June 16, 2009

The Buzz on Bing

Go check out Bing.com - Microsoft's alternative to Google search.

Yes Microsoft is the company we love and hate. And yes a lot of their products may not live up to expectation. BUT. Bing is an internet search engine that is fast, looks good and returns relevant results.

I am impressed and have been using it the past week with satisfaction. See what you think?

Thursday, June 04, 2009

My Emails and Phone Calls...

Do you sell powders???
Why is the price different from the last time I ordered???
Will you send me free samples????
Can you give me free shipping???
I am broke (old/in school/sick/bankrupt) and need to buy some stuff, can you help me out??
Here are my health problems, what would you prescribe???
Will you take my $9.95 phone order? And oh yeah, I need to ask you questions for two hours...

Oh.. and- "where is my (international) package sent via First Class Mail?" (NO tracking and dirt cheap cost)

and... "why did you bill my credit card 2/3/6/gazillion times???""Don't f' with me! I will report you!!" (some customers keep trying to submit orders with incorrect cc info. Over, and over. I finally built a credit card tutorial page just to explain this)

I think I will stop answering the phone and reading emails :-)

Seriously, all in all I have a fantastic customer base. But man oh man the same old crap (from a precious few) sure gets tiresome (and provokes an occasional rant like this).

Had to post this. Enjoy.

Wednesday, June 03, 2009

Curcumin and Chronic Fatigue Syndrome (CFS)

Interesting study (and particularly timely with our Geronova Research R-PLUS with Curcumin on sale):

"Chronic fatigue syndrome affects millions of people in the United States, making it virtually impossible for many of them to hold a full-time or even part-time job, go to school, enjoy their families, or participate in routine or leisure activities. Estimates of the actual number of people who have the disease vary widely, from 500,000 to more than 4 million.

Study of curcumin and chronic fatigue
Oxidative stress is a significant factor in chronic fatigue syndrome, and so ways to reduce it theoretically should also improve symptoms of this complex condition. A study published in the January 2009 issue of Immunobiology reports on mice who were challenged with a stress test for 10 minutes daily for 19 days. Half of the mice were given curcumin and the other half acted as controls.

The control mice showed signs of significant fatigue and had hyperalgesia (increased sensitivity to pain), another common symptom of the syndrome. The mice who were given curcumin showed a significant reduction in fatigue, oxidative stress, and hyperalgesia. The investigators suggest that curcumin may be a valuble option in the treatment of chronic fatigue syndrome.

Curcumin in patients with chronic fatigue syndrome
Along with an increase in oxidative stress, research shows that chronic fatigue syndrome is accompanied by activation of the inflammatory response system, and that a natural agent called nuclear factor kappa beta (NFkappabeta) is the main intracellular mechanism that regulates inflammatory and oxidative stress mediators.

In a Belgian study, researchers studied the possible impact of inhibiting the production of NFkappabeta in patients who had chronic fatigue syndrome. They found that there were significant correlations between the production of NFkappabeta and symptoms typically associated with the syndrome, including muscular tension, fatigue, irritability, depression, a subjective feeling of infection, and aches and pain.

They also discovered that the increase in oxidative stress and inflammation reported in previous studies of chronic fatigue syndrome may be caused by increased production of NFkappabeta. Given these results, the study’s authors suggest that people with chronic fatigue syndrome should be treated with antioxidants that are known to inhibit the production of NFkappabeta, including curcumin, quercetin, lipoic acid, and omega-3 fatty acids.

Curcumin for chronic fatigue syndrome
Curcumin is one of several curcuminoids, the natural pigments that give the spice turmeric its yellow color. It has both antioxidant and anti-inflammatory properties, and as such it is also used to treat arthritis, inflammatory bowel disease, and to help maintain a healthy cardiovascular system."