Monday, September 15, 2008

New Research: L-Carnitine Exerts Blood Pressure Lowering Effects

This new study is very interesting:

"In a study involving rats induced with hypertension (with N(omega)-nitro-L-arginine methyl ester), simultaneous administration of L-carnitine was found to significantly reduce blood pressure. Rats induced with hypertension were found to have increases in plasma levels and heart expression of IL-1beta, IL-6, and TNF-alpha, all of which were reversed by treatment with L-carnitine. In addition, rats induced with hypertension were found to have increases in protein and mRNA expression of ACE and AT1R in the heart; L-carnitine reversed these values. The authors conclude, "The chronic administration of L-carnitine reduces blood pressure and attenuates the inflammatory process associated with arterial hypertension." The authors hypothesize that L-carnitine may partially inactivate the rennin-angiotensin system, "resulting in a reduction in the production and effects of angiotensin II." Additional research is warranted."

Good stuff...